The N2O-CS2 dimer is cross-shaped

A crescent-shaped ALIX dimer targets ESCRT-III CHMP4 filaments.

ALIX recruits ESCRT-III CHMP4 and is involved in membrane remodeling during endosomal receptor sorting, budding of some enveloped viruses, and cytokinesis. We show that ALIX dimerizes via the middle domain (ALIX(-V)) in solution. Structural modeling based on small angle X-ray scattering (SAXS) data reveals an elongated crescent-shaped conformation for dimeric ALIX lacking the proline-rich domai...

The AtMAP65-1 cross-bridge between microtubules is formed by one dimer.

The microtubule-associated protein AtMAP65-1 from Arabidopsis thaliana dimerizes and forms 25 nm cross-bridges between microtubules, but the exact mechanism is unknown. Here, we used the predicted three-dimensional structure of AtMAP65-1 as a basis for analyzing the actual cross-bridging in detail. Fold-recognition predicts that AtMAP65-1 contains four coiled-coil domains and a flexible extende...

Light-Induced N2O Production from a Non-heme Iron–Nitrosyl Dimer

Two non-heme iron-nitrosyl species, [Fe2(N-Et-HPTB)(O2CPh)(NO)2](BF4)2 (1a) and [Fe2(N-Et-HPTB)(DMF)2(NO)(OH)](BF4)3 (2a), are characterized by FTIR and resonance Raman spectroscopy. Binding of NO is reversible in both complexes, which are prone to NO photolysis under visible light illumination. Photoproduction of N2O occurs in high yield for 1a but not 2a. Low-temperature FTIR photolysis exper...

Fun in CS2

We report our experience of including the implementation of a player of a computer game as a programming project in a CS2 course focusing in data structures and algorithms. Every semester, an instructor designs the rules of a game, prepares its visualization, and implements an elementary player with a very simple strategy. The game is then delivered to students who, as a first step in order to ...

The Metal-Catalyzed Cross-Coupling Reactions of n-Butylketene Dimer